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Do not stop taking indinavir , even for a short period of time.

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To reduce the risk of developing drug resistanceall anti-HIV drugs should be taken every day exactly as prescribed and directedIf doses are delayedmissedor not taken as prescribedlevels of indinavir in the blood may fall too lowIf this happensresistant virus can developIf you find you are having problems taking your medications as directedspeak to your doctor and nurse about thisThey can find ways to help you.

Some drugs can interact with indinavirincreasing or decreasing its levels in your bodyIncreased drug levels can cause you to experience side effects or make pre-existing side effects worseOn the other handif drug levels become too lowHIV can develop resistance and your future treatment options may be reduced.

Tell your doctor and pharmacist if you are allergic to indinavirany other medicationsor any of the ingredients in indinavir capsulesAsk your pharmacist for a list of the ingredientstell your doctor if you are taking any of the following medicationsalfuzosinUroxatralalprazolamXanaxamiodaroneCordaroneNexteronePaceronecisapridePropulsidnot available in the U.Sergot-type medications such as dihydroergotamineD.H.E45MigranalergonovineErgotrateergotamineErgomarin Cafergotin Migergotand methylergonovineMetherginelovastatinAltoprevMevacorlurasidoneLatudamidazolamVersedby mouthpimozideOrapsildenafilonly Revatio brand used for lung diseasesimvastatinZocorin Vytorinor triazolamHalcionYour doctor will probably tell you not to take indinavirtell your doctor and pharmacist what other prescription and nonprescription medicationsvitaminsand nutritional supplements you are taking or plan to takeBe sure to mention any of the followingbosentanTracleercalcium-channel blockers such as amlodipineNorvascin Amturnidein Tekamlofelodipinenicardipineand nifedipineAdalatAfeditabProcardiacarbamazepineCarbatrolEpitolEquetroTegretolotherscholesterol-lowering medicationsstatinssuch as atorvastatinLipitorin Caduetand rosuvastatinCrestorclarithromycinBiaxinin PrevPaccolchicineColcrysMitigarein Col-ProbeneciddexamethasonefluconazoleDiflucanfluticasoneFlonaseFloventin Advairin DymistaitraconazoleOnmelSporanoxketoconazoleExtinaNizoralXolegelother medications for HIV including atazanavirReyatazin EvotazdelavirdineRescriptorefavirenzSustivain AtriplanelfinavirViraceptnevirapineViramuneritonavirNorvirin Kaletrain Viekira Pakand saquinavirInvirasemedications for irregular heartbeat such as lidocaineGlydoXylocaineand quinidinein Nuedextamedications that suppress the immune system such as cyclosporineGengrafNeoralSandimmunesirolimusRapamuneand tacrolimusAstagraf XLEnvarsus XRPrografmidazolamVersedby injectioncertain phosphodiesterase inhibitorsPDE-5 inhibitorsused for erectile dysfunction such as sildenafilViagratadalafilAdcircaCialisand vardenafilLevitrain StaxynphenobarbitalphenytoinDilantinPhenytekquetiapineSeroquelrifabutinMycobutinrifampinRifadinRimactanein Rifamatein RifatersalmeterolSereventin Advairtrazodoneand venlafaxineEffexorYour doctor may need to change the doses of your medications or monitor you carefully for side effectsMany other medications may also interact with indinavirso be sure to tell your doctor about all the medications you are takingeven those that do not appear on this listtell your doctor what herbal products you are takingespecially StJohn’s wortif you are taking didanosineVidextake it at least one hour before or after indinavirtell your doctor if you have or have ever had hemophiliableeding disorder in which the blood does not clot properlydiabetesor kidney or liver diseasetell your doctor if you are pregnantplan to become pregnantor are breastfeedingIf you become pregnant while taking indinavircall your doctorYou should not breastfeed if you are infected with HIV or if you are taking indinaviryou should know that your body fat may increase or move to different areas of your body such as your breastsupper backneckchestand stomach areaLoss of fat from the legsarmsand face can also happenyou should know that you may experience hyperglycemiaincreases in your blood sugarwhile you are taking this medicationeven if you do not already have diabetesTell your doctor immediately if you have any of the following symptoms while you are taking indinavirextreme thirstfrequent urinationextreme hungerblurred visionor weaknessIt is very important to call your doctor as soon as you have any of these symptomsbecause high blood sugar that is not treated can cause a serious condition called ketoacidosisKetoacidosis may become life-threatening if it is not treated at an early stageSymptoms of ketoacidosis include dry mouthnausea and vomitingshortness of breathbreath that smells fruityand decreased consciousnessyou should know that while you are taking medications to treat HIV infectionyour immune system may get stronger and begin to fight other infections that were already in your bodyThis may cause you to develop symptoms of those infectionsIf you have new or worsening symptoms at anytime during your treatment with indinavirbe sure to tell your doctor.

Patients should be advised to remain under the care of a physician when using CRIXIVAN and should not modify or discontinue treatment without first consulting the physicianThereforeif a dose is missedpatients should take the next dose at the regularly scheduled time and should not double this doseTherapy with CRIXIVAN should be initiated and maintained at the recommended dosage.

To reduce the risk of developing drug resistanceall anti-HIV drugs should be taken every day exactly as prescribed and directedIf doses are delayedmissedor not taken as prescribedlevels of indinavir in the blood may fall too lowIf this happensresistant virus can developIf you find you are having problems taking your medications as directedspeak to your doctor and nurse about thisThey can find ways to help you.

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indinavir has no effects on delavirdine pharmacokinetics.

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