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The number of adverse effects reported from clinical use of rocaltrol over a period of 15 years in all indications is very low with each individual effect, including hypercalcaemia, occurring at a rate of 0.

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Although most of the side effects listed below don’t happen very oftenthey could lead to serious problems if you do not seek medical attention.

Rocaltrolcalcitriolis the most potent metabolite of vitamin D availableThe administration of Rocaltrolcalcitriolto patients in excess of their daily requirements can cause hypercalcemiahypercalciuriaand hyperphosphatemiaThereforepharmacologic doses of vitamin D and its derivatives should be withheld during Rocaltrolcalcitrioltreatment to avoid possible additive effects and hypercalcemiaIf treatment is switched from ergocalciferolvitamin D 2to calcitriolit may take several months for the ergocalciferol level in the blood to return to the baseline valuesee OVERDOSAGE

The early and late signs and symptoms of vitamin D intoxication associated with hypercalcemia include:

During the titration period of treatment with Rocaltrolcalcitriolserum calcium levels should be checked at least twice weeklyWhen the optimal dosage of Rocaltrolcalcitriolhas been determinedserum calcium levels should be checked every monthor as given below for individual indicationsSamples for serum calcium estimation should be taken without a tourniquet.

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