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Concomitant administration of immediate-release form with a phosphodiesterase-5PDE-5inhibitor can result in additive blood pressure lowering effects and symptomatic hypotension.

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Conventional doxazosin has been administered without any adverse drug interactions in clinical experience with thiazide diureticsfrusemidebeta-blocking agentsnon-steroidal anti-inflammatory drugsantibioticsoral hypoglycaemic drugsuricosuric agentsor anticoagulantsHoweverdata from formal drug/drug interaction studies are not present.

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