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Jay WMarksMDis a board-certified internist and gastroenterologistHe graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

EVISTAraloxifene hydrochlorideis an estrogen agonist/antagonistcommonly referred to as a selective estrogen receptor modulatorSERMthat belongs to the benzothiophene class of compoundsThe chemical structure is:

EVISTA should not be used for the primary or secondary prevention of cardiovascular diseaseIn a clinical trial of postmenopausal women with documented coronary heart disease or at increased risk for coronary eventsno cardiovascular benefit was demonstrated after treatment with raloxifene for 5 yearssee Clinical Studies

Lipid-Lowering AgentsConcomitant administration of EVISTA with lipid-lowering agents has not been studied.

EVISTA should be used with caution in patients with moderate or severe renal impairmentSafety and efficacy have not been established in patients with moderate or severe renal impairmentsee CLINICAL PHARMACOLOGY

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evista can be concomitantly administered with ampicillin, amoxicillin, antacids, corticosteroids, and digoxin see clinical pharmacology 12.

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