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Decreased hemoglobin and hematocritabnormalities in alkaline phosphataseSGOTASTSGPTALTLDHbilirubinBUNCoombs testelevated serum glucosewhite blood cellsbacteriaand blood in the urine.

In clinical pharmacologic studiessimultaneous administration of carbidopa and levodopa produced greater urinary excretion of levodopa in proportion to the excretion of dopamine than administration of the two drugs at separate times.

Since levodopa competes with certain amino acids for transport across the gut wallthe absorption of levodopa may be impaired in some patients on a high protein diet.

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